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SEVERE COMBINED IMMUNODEFICIENCY DISEASE
| Pronunciation (US): |  | (GB): | |
I. (noun)
Sense 1
Meaning:
A congenital disease affecting T cells that can result from a mutation in any one of several different genes; children with it are susceptible to infectious disease; if untreated it is lethal within the first year or two of life
Synonyms:
SCID; severe combined immunodeficiency; severe combined immunodeficiency disease
Classified under:
Nouns denoting stable states of affairs
Hypernyms ("severe combined immunodeficiency disease" is a kind of...):
immunodeficiency (immunological disorder in which some part of the body's immune system is inadequate and resistance to infectious diseases is reduced)
monogenic disease; monogenic disorder (an inherited disease controlled by a single pair of genes)
Hyponyms (each of the following is a kind of "severe combined immunodeficiency disease"):
ADA-SCID (SCID resulting from mutation of a gene that codes for adenosine deaminase)
X-linked SCID; X-SCID (SCID in male children resulting from mutation of a gene that codes for a protein on the surface of T cells that allows them to develop a growth factor receptor)
