Health / Medical Topics

    SIAH2 wt Allele

    Human SIAH2 wild-type allele is located in the vicinity of 3q25 and is approximately 22 kb in length. This allele, which encodes E3 ubiquitin-protein ligase SIAH2 protein, is involved in the mediation of ubiquitination. Expression of the gene may play a role in the development or progression of metastatic prostate neuroendocrine tumor. (NCI Thesaurus)




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