Health / Medical Topics

    SMAD3 wt Allele

    Human SMAD3 wild-type allele is located in the vicinity of 15q22.33 and is approximately 130 kb in length. This allele, which encodes mothers against decapentaplegic homolog 3 protein, plays a role in the transcriptional regulation of the cellular response to transforming growth factor-beta. (NCI Thesaurus)




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