Health / Medical Topics

    SRC Family Gene

    Definition 1

    A family of genes that encode structurally similar non-receptor tyrosine kinases that play a role in intracellular signaling. Mutation of genes in this family is associated with cancer. (NCI Thesaurus)

    Definition 2

    Retrovirus-associated DNA sequences (src) originally isolated from the Rous sarcoma virus (RSV). The proto-oncogene src (c-src) codes for a protein that is a member of the tyrosine kinase family and was the first proto-oncogene identified in the human genome. The human c-src gene is located at 20q12-13 on the long arm of chromosome 20. (NLM, Medical Subject Headings)




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