Health / Medical Topics

    TOPBP1 Gene

    This gene is involved in DNA replication and apoptosis regulation. (NCI Thesaurus)




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    Human TOP3B wild-type allele is located in the vicinity of 22q11.22 and is approximately 26 kb in length. This allele, which encodes…
    This gene is involved in DNA recombination, cellular aging and the maintenance of genome integrity.
    Human TOP3A wild-type allele is located within 17p12-p11.2 and is approximately 41 kb in length. This allele, which encodes DNA topoisomerase 3-alpha…
    This gene plays a role in the regulation of DNA topology and recombination in somatic cells.
    Human TOP2B wild-type allele is located within 3p24 and is approximately 66 kb in length. This allele, which encodes DNA topoisomerase 2-beta…
    This gene is involved in chromosome recombination, DNA replication and the regulation of DNA topology during transcription.

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