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TRICYCLIC ANTIDEPRESSANT
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I. (noun)
Sense 1
Meaning:
An antidepressant drug that acts by blocking the reuptake of norepinephrine and serotonin and thus making more of those substances available to act on receptors in the brain
Synonyms:
tricyclic; tricyclic antidepressant; tricyclic antidepressant drug
Classified under:
Nouns denoting man-made objects
Hypernyms ("tricyclic antidepressant" is a kind of...):
antidepressant; antidepressant drug (any of a class of drugs used to treat depression; often have undesirable side effects)
Hyponyms (each of the following is a kind of "tricyclic antidepressant"):
amitriptyline; amitriptyline hydrochloride; Elavil (a tricyclic antidepressant drug (trade name Elavil) with serious side effects; interacts with many other medications)
clomipramine (a tricyclic antidepressant drug)
desipramine (a tricyclic antidepressant drug that activates the psychomotor system)
Adapin; doxepin; doxepin hydrochloride; Sinequan (a tricyclic antidepressant (trade names Adapin and Sinequan) with numerous side effects (dry mouth and sedation and gastrointestinal disturbances))
Imavate; imipramine; impramine hydrochloride; Tofranil (a tricyclic antidepressant (trade names Imavate and Tofranil) used to treat clinical depression)
nortriptyline; Pamelor (a tricyclic antidepressant drug (trade name Pamelor) used along with psychotherapy to treat dysthymic depression; may interact dangerously if taken with other drugs)
protriptyline (tricyclic antidepressant used to treat clinical depression)
Surmontil; trimipramine (tricyclic antidepressant drug (trade name Surmontil) used to treat depression and anxiety and (sometimes) insomnia)
Context examples:
A tricyclic antidepressant agent used for short-term treatment of various forms of depression.
(Nortriptyline, NCI Thesaurus)
A tricyclic antidepressant that acts by reducing the re-uptake of norepinephrine and serotonin in the central nervous system, thereby enhancing the effects of these neurotransmitters.
(Clomipramine, NCI Thesaurus)
This agent does not inhibit monoamine oxidase and, compared to classical tricyclic antidepressants, is a weak blocker of the neuronal uptake of serotonin and norepinephrine.
(Bupropion, NCI Thesaurus)
Clomipramine hydrochloride is a tricyclic antidepressant that acts by reducing the re-uptake of norepinephrine and serotonin in the central nervous system, thereby enhancing the effects of these neurotransmitters.
(Clomipramine Hydrochloride, NCI Thesaurus)
The hydrochloride salt form of desipramine, a secondary amine tricyclic antidepressant (TCA).
(Desipramine Hydrochloride, NCI Thesaurus)
