Library / English Dictionary

    ANTIDEPRESSANT

    Pronunciation (US): Play  (GB): Play

     I. (noun) 

    Sense 1

    Meaning:

    Any of a class of drugs used to treat depression; often have undesirable side effectsplay

    Synonyms:

    antidepressant; antidepressant drug

    Classified under:

    Nouns denoting man-made objects

    Hypernyms ("antidepressant" is a kind of...):

    medicament; medication; medicinal drug; medicine ((medicine) something that treats or prevents or alleviates the symptoms of disease)

    Hyponyms (each of the following is a kind of "antidepressant"):

    MAOI; monoamine oxidase inhibitor (any of a group of antidepressant drugs that inhibit the action of monoamine oxidase in the brain and so allow monoamines to accumulate)

    nefazodone; Serzone (an antidepressant drug (trade name Serzone))

    nontricyclic; nontricyclic antidepressant; nontricyclic antidepressant drug; nontricyclic drug (a class of antidepressant drugs that are not tricyclic drugs and do not act by inhibiting MAO)

    Edronax; reboxetine (an antidepressant drug that blocks the reuptake of norepinephrine)

    selective-serotonin reuptake inhibitor; SSRI (an antidepressant drug that acts by blocking the reuptake of serotonin so that more serotonin is available to act on receptors in the brain)

    tricyclic; tricyclic antidepressant; tricyclic antidepressant drug (an antidepressant drug that acts by blocking the reuptake of norepinephrine and serotonin and thus making more of those substances available to act on receptors in the brain)

    maleate (a salt or ester of maleic acid; used as a nontricyclic antidepressant drug for psychomotor activation)

    Credits

     Context examples: 

    It is a type of tricyclic antidepressant.

    (Aventyl, NCI Dictionary)

    The molecular mechanism of the antidepressant effect of bupropion is unknown.

    (Bupropion, NCI Thesaurus)

    It belongs to the family of drugs called antidepressants.

    (Bupropion, NCI Dictionary)

    A synthetic tetracyclic derivative of the piperazino-azepines with antidepressant activity.

    (Mirtazapine, NCI Thesaurus)

    It belongs to the family of drugs called antidepressant agents.

    (Mirtazapine, NCI Dictionary)

    The hydrochloride salt form of pargyline, a monoamine oxidase (MAO) inhibitor with antidepressant activity.

    (Pargyline Hydrochloride, NCI Thesaurus)

    Increased receptor stimulation may cause downregulation of central receptors which may attribute to pargyline's antidepressant effect.

    (Pargyline, NCI Thesaurus)

    The hydrochloride salt form of paroxetine, a phenylpiperidine derivative and a selective serotonin reuptake inhibitor (SSRI) with antidepressant and anxiolytic properties.

    (Paroxetine hydrochloride, NCI Thesaurus)

    The mesylate salt form of paroxetine, a phenylpiperidine derivative and a selective serotonin reuptake inhibitor (SSRI) with antidepressant and anxiolytic properties.

    (Paroxetine Mesylate, NCI Thesaurus)

    Increased serotonin levels augment the antidepressant action of selective serotonin reuptake inhibitors and monoamine oxidase inhibitors.

    (Pindolol, NCI Thesaurus)


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