| Health / Medical Topics |
Vindesine
Pronunciation
Definition 1
An anticancer drug that belongs to the family of plant drugs called vinca alkaloids. (NCI Dictionary)
Definition 2
A synthetic derivative of vinblastine, a naturally occurring vinca alkaloid. Vindesine binds to and stabilizes tubulin, thereby interrupting tubulin polymerization and preventing the formation of the mitotic spindle and cell division; treated cells are unable to undergo mitosis and are arrested in metaphase. This agent also disrupts macromolecular synthesis. (NCI Thesaurus)
YOU MAY ALSO LIKE
Encoded by a single human tumor suppressor VCL Gene, Vinculin contains 1,066 amino acids with strong similarity to other vinculins and…
A regimen containing vincristine, dactinomycin and cyclophosphamide used for the treatment of intermediate-risk childhood rhabdomyosarcoma.
A regimen containing vincristine and dactinomycin used for the treatment of low-risk childhood rhabdomyosarcoma.
A form of the anticancer drug vincristine sulfate that is contained inside very tiny, fat-like particles. It may have fewer side effects…
A drug used to treat acute leukemia. It is used in combination with other drugs to treat Hodgkin disease, non-Hodgkin lymphoma, rhabdomyosarcoma,…
A liposomal formulation of Vincristine designed to reduce toxicity and improve efficacy. Vincristine binds irreversibly to microtubules and spindle proteins in…
