Health / Medical Topics

    Apoptosis Regulator Bcl-2

    Definition 1

    Apoptosis regulator Bcl-2 (239 aa, ~26 kDa) is encoded by the human BCL2 gene. This protein plays a role in cellular survival. (NCI Thesaurus)

    Definition 2

    A protein that helps control whether a cell lives or dies by blocking a type of cell death called apoptosis. The gene for BCL2 is found on chromosome 18, and transfer of the BCL2 gene to a different chromosome is seen in many B-cell leukemias and lymphomas. This causes the BCL2 protein to be made in larger amounts, which may keep cancer cells from dying. (NCI Dictionary)




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