HMGA2/ALDH2 Fusion Gene

A fusion gene that results from paracentric inversion of chromosome 12 which juxtaposes the first 3 exons of the HGMA2 gene with exon 13 and part of the 3' untranslated region of the ALDH2 gene. This fusion is associated with benign uterine leiomyoma. (NCI Thesaurus)

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HMGA2 wt Allele

Human HMGA2 wild-type allele is located within 12q15 and is approximately 142 kb in length. This allele, which encodes high mobility group…

HMGA2 Gene

This gene is involved in chromatin organization and regulation of gene transcription. It also plays a role in development.

HMGA1 wt Allele

Human HMGA1 wild-type allele is located within 6p21 and is approximately 9 kb in length. This allele, which encodes high mobility group…

HMGA1 Gene

This gene plays a role in a number of cellular processes including apoptosis, chromatin organization and transcriptional regulation.

HMGA1

A protein that binds to the DNA and certain proteins in chromosomes. It is involved in many functions in the cell, and…

HMGA Family Protein

Members of this family of high mobility group (HMG) proteins participate in a wide variety of nuclear processes ranging from chromosome and…