Health / Medical Topics

    HMGA2/CCNB1IP1 Fusion Gene

    A fusion gene that results from a chromosomal translocation t(12;14) which fuses exons 1 and 2 of the HMGA2 gene to the 3' portion of the CCNB1IP1 gene. This rearrangement is associated with uterine leiomyoma. (NCI Thesaurus)




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    A fusion gene that results from paracentric inversion of chromosome 12 which juxtaposes the first 3 exons of the HGMA2 gene with…
    Human HMGA2 wild-type allele is located within 12q15 and is approximately 142 kb in length. This allele, which encodes high mobility group…
    This gene is involved in chromatin organization and regulation of gene transcription. It also plays a role in development.
    Human HMGA1 wild-type allele is located within 6p21 and is approximately 9 kb in length. This allele, which encodes high mobility group…
    This gene plays a role in a number of cellular processes including apoptosis, chromatin organization and transcriptional regulation.

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