Health / Medical Topics

    Oncogene KIT

    Cloned cancer gene for Familial gastrointestinal stromal tumors (GIST), KIT proto-oncogene encodes a putative transmembrane receptor tyrosine kinase for stem cell factor and is critical in the development of pluripotent hematopoietic stem cells, migrating embryonic melanoblasts, and primordial germ cells. The human proto-oncogene is located at 4q12. (NCI Thesaurus)




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