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Malignant Giant Cell Tumor of Tendon Sheath
Definition 1
An uncommon malignant tumor arising from the tendon sheath. Morphologically, it is characterized by the presence of a cellular infiltrate reminiscent of a giant cell tumor with prominent malignant characteristics. Recurrent giant cell tumors with a sarcomatous dedifferentiation are included in this category as well. (NCI Thesaurus)
Definition 2
A benign giant cell tumor of tendon sheath characterized by a proliferation of synovial-like mononuclear giant cells and multinucleated giant cells with areas of overt malignancy. Alternatively, this may tumor may present as a sarcoma recurring in the site of a previously diagnosed typical giant cell tumor. (NCI Thesaurus)
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