Health / Medical Topics

    Small Inducible Cytokine A7

    Small Inducible Cytokine A7, encoded by the CCL7 gene, is a secreted chemokine which attracts macrophages during inflammation and metastasis. It is a member of the C-C subfamily of chemokines which are characterized by having two adjacent cysteine residues. The protein is an in vivo substrate of matrix metalloproteinase 2, an enzyme which degrades components of the extracellular matrix. (NCI Thesaurus/LocusLink)




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